Allergy diagnosis: In Search of the allergen

Occur for unknown reasons, itching, redness, swelling or pain in the gastrointestinal tract on could be an allergic reaction is the cause. One suspects an allergy, first a visit to the doctor is advisable. Depending on which organs are affected, the subsequent treatment is continued by a specialist in the relevant field.Case historyA detailed medical history (survey of medical history) is the basis for the diagnosis. It will be in conversation, partly resolved including the use of questionnaires, for example, any genetic predisposition, timing and possible triggers of symptoms and contact with potential allergens. In allergy diagnosis according to a history of various skin, blood and provocation tests identify different allergy-causing substances.Skin testsUsually are preceded by a skin test. This brings the allergist several known allergens in concentrated form in contact with the skin. Depending on how the skin comes into contact, one distinguishes between prick test, scratch test, Intracutantest, rubbing test and patch test.Blood testsBlood tests can complement skin testing. With these blood tests can determine the total content of immunoglobulin E (IgE) and allergen-specific IgE. Blood tests are also suitable for patients in whom no skin tests can be performed (eg, severe skin disease). A standard test for determining the concentration of allergen-specific antibodies in the blood is the radio-Allergy-Sorbent Test (RAST).Provocation testsCould these tests with the allergens are not clearly identified, may shed further light provocation tests. In these tests, the allergen in question be directly applied to the mucous membranes or injected, inhaled or swallowed. Since provocation tests have some risks (in the worst case, anaphylactic shock) for the patients recover, they should be performed only in exceptional cases and only under medical supervision in hospital or specialized clinics. (Ah)